Chicago's new bench is going to have to develop chemistry together, as the Bulls are forced to shuffle their starting lineup and substitutions in Rose's absence.
Memphis head coach Lionel Hollins noted before Tuesday's game that it will take awhile for the chemistry to develop in Chicago.
"What probably will affect them more than Derrick Rose being out is all the new players they have to mesh together," Hollins said. "That's a huge task for Tom to have to mesh these guys because they have a very good defensive philosophy and a very good defensive team. So now, you're adding all these guys, and it takes time."
The Bulls have six preseason games remaining, as they look to develop chemistry prior to the regular season. The Bulls will take on the Cleveland Cavaliers on Friday, before headed to Minnesota to take on the Timberwolves on Saturday.
Chicago's regular season opener is slated for Wednesday, Oct. 31, at home against the Sacramento Kings.