No. 22 Notre Dame handled the Purdue Boilermakers with little problem, 81-68, when the four main college basketball programs in the state of Indiana traveled to Indianapolis' Bankers Life Fieldhouse on Saturday. The same could not be said for No. 1 Indiana.

Notre Dame trailed for only a few minutes before mounting a 17-6 run early in the first half and never looked back, leading for the rest of the game. Jack Cooley led the way for the Fighting Irish, scoring 18 points with nine rebounds and three blocks. Eric Atkins and Pat Connaughton contributes as well, scoring 17 points and 16 points, respectively.

The Fighting Irish took care of their opponent, something the top-ranked Indiana Hoosiers could not do on the same floor earlier that day. The Butler Bulldogs fought and scrapped their way to a 88-86 overtime victory, defeating the nation's No. 1 team for the first time in school history.

Other games regional games scores are below.

Illinois-Chicago 74, Eastern Michigan 48

Loyola (IL) 59, Mississippi St. 51

Southern Illinois 72, Green Bay 70

No. 10 Illinois faces Eastern Kentucky on Sunday evening in Champaign, while Northwestern plays again on Monday against Texas State.